Influence of androgenic blockade with flutamide on pain behaviour and expression of the genes that encode the NaV1.7 and NaV1.8 voltage-dependent sodium channels in a rat model of postoperative pain

BACKGROUND: Experimental studies suggest that testosterone reduces the nociceptive response after inflammatory and neuropathic stimuli, however the underlying mechanisms have not been fully elucidated. The aims of this study were to evaluate the effect of peripheral blockade of testosterone on pain...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Transl Med
Hauptverfasser: Barbosa Neto, José Osvaldo, Garcia, João Batista Santos, Cartágenes, Maria do Socorro de Souza, Amaral, Andressa Godoy, Onuchic, Luiz Fernando, Ashmawi, Hazem Adel
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712891/
https://ncbi.nlm.nih.gov/pubmed/31455381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-2031-z
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge