Systematic evaluation and validation of reference and library selection methods for deconvolution of cord blood DNA methylation data

BACKGROUND: Umbilical cord blood (UCB) is commonly used in epigenome-wide association studies of prenatal exposures. Accounting for cell type composition is critical in such studies as it reduces confounding due to the cell specificity of DNA methylation (DNAm). In the absence of cell sorting inform...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Gervin, Kristina, Salas, Lucas A., Bakulski, Kelly M., van Zelm, Menno C., Koestler, Devin C., Wiencke, John K., Duijts, Liesbeth, Moll, Henriëtte A., Kelsey, Karl T., Kobor, Michael S., Lyle, Robert, Christensen, Brock C., Felix, Janine F., Jones, Meaghan J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712867/
https://ncbi.nlm.nih.gov/pubmed/31455416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0717-y
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