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Tracing human stem cell lineage during development using DNA methylation
Stem cell maturation is a fundamental, yet poorly understood aspect of human development. We devised a DNA methylation signature deeply reminiscent of embryonic stem cells (a fetal cell origin signature, FCO) to interrogate the evolving character of multiple human tissues. The cell fraction displayi...
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| Publicat a: | Genome Res |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6120629/ https://ncbi.nlm.nih.gov/pubmed/30072366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.233213.117 |
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