Sensitization of Tumors for Attack by Virus-Specific CD8+ T-Cells Through Antibody-Mediated Delivery of Immunogenic T-Cell Epitopes

Anti-tumor immunity is limited by a number of factors including the lack of fully activated T-cells, insufficient antigenic stimulation and the immune-suppressive tumor microenvironment. We addressed these hurdles by developing a novel class of immunoconjugates, Antibody-Targeted Pathogen-derived Pe...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Sefrin, Julian P., Hillringhaus, Lars, Mundigl, Olaf, Mann, Karin, Ziegler-Landesberger, Doris, Seul, Heike, Tabares, Gloria, Knoblauch, Dominic, Leinenbach, Andreas, Friligou, Irene, Dziadek, Sebastian, Offringa, Rienk, Lifke, Valeria, Lifke, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712545/
https://ncbi.nlm.nih.gov/pubmed/31555260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01962
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge