Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene

Here, we investigated the clinicopathological and mutation profiles of colorectal cancer (CRC) with POLE mutations. Whole‐exome sequencing was performed in 910 surgically resected primary CRCs. Tumors exceeding 500 counts of nonsynonymous single nucleotide variants (SNVs) were classified as hypermut...

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Foilsithe in:Cancer Med
Main Authors: Hino, Hitoshi, Shiomi, Akio, Kusuhara, Masatoshi, Kagawa, Hiroyasu, Yamakawa, Yushi, Hatakeyama, Keiichi, Kawabata, Takanori, Oishi, Takuma, Urakami, Kenichi, Nagashima, Takeshi, Kinugasa, Yusuke, Yamaguchi, Ken
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2019
Ábhair:
Clinical Cancer Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712448/
https://ncbi.nlm.nih.gov/pubmed/31240875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2344
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