SerpinB2 inhibits migration and promotes a resolution phase signature in large peritoneal macrophages

SerpinB2 (plasminogen activator inhibitor type 2) has been called the “undecided serpin” with no clear consensus on its physiological role, although it is well described as an inhibitor of urokinase plasminogen activator (uPA). In macrophages, pro-inflammatory stimuli usually induce SerpinB2; howeve...

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Udgivet i:Sci Rep
Main Authors: Schroder, Wayne A., Hirata, Thiago D., Le, Thuy T., Gardner, Joy, Boyle, Glen M., Ellis, Jonathan, Nakayama, Eri, Pathirana, Dilan, Nakaya, Helder I., Suhrbier, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712035/
https://ncbi.nlm.nih.gov/pubmed/31455834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48741-w
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