CCR2 Deficiency Promotes Exacerbated Chronic Erosive Neutrophil-Dominated Chikungunya Virus Arthritis

Chikungunya virus (CHIKV) is a member of a globally distributed group of arthritogenic alphaviruses that cause weeks to months of debilitating polyarthritis/arthralgia, which is often poorly managed with current treatments. Arthritic disease is usually characterized by high levels of the chemokine C...

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Detalhes bibliográficos
Main Authors: Poo, Yee Suan, Nakaya, Helder, Gardner, Joy, Larcher, Thibaut, Schroder, Wayne A., Le, Thuy T., Major, Lee D., Suhrbier, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054367/
https://ncbi.nlm.nih.gov/pubmed/24696480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03364-13
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