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Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis

Expression of SerpinB2 (plasminogen activator inhibitor type 2/PAI-2) by certain cancers is associated with a favorable prognosis. Although tumor-associated host tissues can express SerpinB2, no significant differences in the growth of a panel of different tumors in SerpinB2(−/−) and SerpinB2(+/+) m...

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Detalhes bibliográficos
Main Authors: Schroder, Wayne A, Major, Lee D, Le, Thuy T, Gardner, Joy, Sweet, Matthew J, Janciauskiene, Sabina, Suhrbier, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101741/
https://ncbi.nlm.nih.gov/pubmed/24644264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.229
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