3.1Å structure of yeast RNA polymerase II elongation complex stalled at a cyclobutane pyrimidine dimer lesion solved using streptavidin affinity grids

Despite significant advances in all aspects of single particle cryo-electron microscopy (cryo-EM), specimen preparation still remains a challenge. During sample preparation, macromolecules interact with the air-water interface, which often leads to detrimental effects such as denaturation or adoptio...

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Veröffentlicht in:J Struct Biol
Hauptverfasser: Lahiri, Indrajit, Xu, Jun, Han, Bong Gyoon, Oh, Juntaek, Wang, Dong, DiMaio, Frank, Leschziner, Andres E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711803/
https://ncbi.nlm.nih.gov/pubmed/31200019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2019.06.004
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