Degenerate intervertebral disc‐like pH induces a catabolic mechanoresponse in human nucleus pulposus cells

Mechanical stimulation is known to influence intervertebral disc (IVD) cell behavior and function, but the effect on disc cells is routinely considered in isolation from other microenvironmental factors. Acidic pH has been shown to be a prominent and detrimental microenvironmental factor present in...

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Veröffentlicht in:JOR Spine
Hauptverfasser: Hodson, Nathan W., Patel, Sonal, Richardson, Stephen M., Hoyland, Judith A., Gilbert, Hamish T. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2018
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711490/
https://ncbi.nlm.nih.gov/pubmed/31463436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1004
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