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Degenerate intervertebral disc‐like pH induces a catabolic mechanoresponse in human nucleus pulposus cells

Mechanical stimulation is known to influence intervertebral disc (IVD) cell behavior and function, but the effect on disc cells is routinely considered in isolation from other microenvironmental factors. Acidic pH has been shown to be a prominent and detrimental microenvironmental factor present in...

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Udgivet i:JOR Spine
Main Authors: Hodson, Nathan W., Patel, Sonal, Richardson, Stephen M., Hoyland, Judith A., Gilbert, Hamish T. J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711490/
https://ncbi.nlm.nih.gov/pubmed/31463436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1004
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