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Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
Mitochondria undergo fission and fusion to maintain homeostasis, and tumors exhibit the dysregulation of mitochondrial dynamics. We recently demonstrated that ectopic HRas(G12V) promotes mitochondrial fragmentation and tumor growth through Erk phosphorylation of the mitochondrial fission GTPase Dyna...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6711191/ https://ncbi.nlm.nih.gov/pubmed/31412251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.031 |
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