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Discovery of new butyrylcholinesterase inhibitors via structure-based virtual screening

Butyrylcholinesterase (BChE) plays an important role in the progression of the Alzheimer’s disease. In this study, we used a structure-based virtual screening (VS) approach to discover new BChE inhibitors. A ligand database was filtered and docked to the BChE protein using Glide program. The outcome...

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Bibliografske podrobnosti
izdano v:J Enzyme Inhib Med Chem
Main Authors: Atatreh, Noor, Al Rawashdah, Sara, Al Neyadi, Shaikha S., Abuhamdah, Sawsan M., Ghattas, Mohammad A.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711031/
https://ncbi.nlm.nih.gov/pubmed/31347933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1644329
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