Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cells

BACKGROUND: While smoking is known to associate with development of multiple diseases, the underlying mechanisms are still poorly understood. Tobacco smoking can modify the chemical integrity of DNA leading to changes in transcriptional activity, partly through an altered epigenetic state. We aimed...

詳細記述

保存先:
書誌詳細
出版年:EBioMedicine
主要な著者: Ringh, Mikael V., Hagemann-Jensen, Michael, Needhamsen, Maria, Kular, Lara, Breeze, Charles E., Sjöholm, Louise K., Slavec, Lara, Kullberg, Susanna, Wahlström, Jan, Grunewald, Johan, Brynedal, Boel, Liu, Yun, Almgren, Malin, Jagodic, Maja, Öckinger, Johan, Ekström, Tomas J.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2019
主題:
Research paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710853/
https://ncbi.nlm.nih.gov/pubmed/31303497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.07.006
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