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Population pharmacokinetics of treosulfan in paediatric patients undergoing hematopoietic stem cell transplantation

AIMS: Treosulfan is an alkylating agent increasingly used prior to haematopoietic stem cell transplantation. The aim of this study was to develop a population pharmacokinetic (PK) model of treosulfan in paediatric haematopoietic stem cell transplantation recipients and to explore the effect of poten...

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Publicat a:Br J Clin Pharmacol
Autors principals: van der Stoep, M. Y. E. C., Zwaveling, J., Bertaina, A., Locatelli, F., Guchelaar, H. J., Lankester, A. C., Moes, D. J. A. R.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710524/
https://ncbi.nlm.nih.gov/pubmed/31144349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13995
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