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Population pharmacokinetics of treosulfan and development of a limited sampling strategy in children prior to hematopoietic stem cell transplantation

PURPOSE: There is an increasing interest in use of treosulfan (TREO), a structural analogue of busulfan, as an agent in conditioning regimens prior to hematopoietic stem cell transplantation (HSCT), both in pediatric and adult populations. The aim of this study was to develop a population pharmacoki...

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Detalhes bibliográficos
Publicado no:Eur J Clin Pharmacol
Main Authors: Danielak, Dorota, Twardosz, Jadwiga, Kasprzyk, Anna, Wachowiak, Jacek, Kałwak, Krzysztof, Główka, Franciszek
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748442/
https://ncbi.nlm.nih.gov/pubmed/28975382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-017-2344-x
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