EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells

The Polycomb group of proteins is required for the proper orchestration of gene expression due to its role in maintaining transcriptional silencing. It is composed of several chromatin modifying complexes, including Polycomb Repressive Complex 2 (PRC2), which deposits H3K27me2/3. Here, we report the...

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Publié dans:Nat Commun
Auteurs principaux: Ragazzini, Roberta, Pérez-Palacios, Raquel, Baymaz, Irem H., Diop, Seynabou, Ancelin, Katia, Zielinski, Dina, Michaud, Audrey, Givelet, Maëlle, Borsos, Mate, Aflaki, Setareh, Legoix, Patricia, Jansen, Pascal W. T. C., Servant, Nicolas, Torres-Padilla, Maria-Elena, Bourc’his, Deborah, Fouchet, Pierre, Vermeulen, Michiel, Margueron, Raphaël
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710278/
https://ncbi.nlm.nih.gov/pubmed/31451685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11800-x
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