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DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination
DNA methylation is essential for protecting the mammalian germline against transposons. When DNA methylation-based transposon control is defective, meiotic chromosome pairing is consistently impaired during spermatogenesis: How and why meiosis is vulnerable to transposon activity is unknown. Using t...
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| Publicado no: | Genes Dev |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4495397/ https://ncbi.nlm.nih.gov/pubmed/26109049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.257840.114 |
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