DNA methylation restrains transposons from adopting a chromatin signature permissive for meiotic recombination

DNA methylation is essential for protecting the mammalian germline against transposons. When DNA methylation-based transposon control is defective, meiotic chromosome pairing is consistently impaired during spermatogenesis: How and why meiosis is vulnerable to transposon activity is unknown. Using t...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Genes Dev
Autors principals: Zamudio, Natasha, Barau, Joan, Teissandier, Aurélie, Walter, Marius, Borsos, Maté, Servant, Nicolas, Bourc'his, Déborah
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495397/
https://ncbi.nlm.nih.gov/pubmed/26109049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.257840.114
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars