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Securing the Payload, Finding the Cell, Avoiding the Endosome: Peptide-Targeted, Fusogenic Porous Silicon Nanoparticles for Delivery of siRNA
Despite the promise of RNAi therapeutics, the delivery of oligonucleotides selectively to diseased tissues in the body, and specifically to the cellular location in the tissues needed to provide optimal therapeutic outcome, remains a significant challenge. Here, key material properties and biologica...
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| Publicado no: | Adv Mater |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6710136/ https://ncbi.nlm.nih.gov/pubmed/31267590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.201902952 |
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