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Porous silicon–graphene oxide core–shell nanoparticles for targeted delivery of siRNA to the injured brain
We report the synthesis, characterization, and assessment of a nanoparticle-based RNAi delivery platform that protects siRNA payloads against nuclease-induced degradation and efficiently delivers them to target cells. The nanocarrier is based on biodegradable mesoporous silicon nanoparticles (pSiNPs...
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| Publié dans: | Nanoscale Horiz |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5935492/ https://ncbi.nlm.nih.gov/pubmed/29732165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6NH00082G |
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