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Tbx1 and Foxi3 genetically interact in the pharyngeal pouch endoderm in a mouse model for 22q11.2 deletion syndrome
We investigated whether Tbx1, the gene for 22q11.2 deletion syndrome (22q11.2DS) and Foxi3, both required for segmentation of the pharyngeal apparatus (PA) to individual arches, genetically interact. We found that all Tbx1(+/-);Foxi3(+/-) double heterozygous mouse embryos had thymus and parathyroid...
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| Publicado no: | PLoS Genet |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6709926/ https://ncbi.nlm.nih.gov/pubmed/31412026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008301 |
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