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Signaling Pathways Regulating Hematopoietic Stem Cell and Progenitor Aging

PURPOSE OF REVIEW: Functional decline of hematopoiesis that occurs in the elderly, or in patients who receive therapies that trigger cellular senescence effects, results in a progressive reduction in the immune response and an increased incidence of myeloid malignancy. Intracellular signals in hemat...

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Detalhes bibliográficos
Publicado no:Curr Stem Cell Rep
Main Authors: Singh, Abhishek K., Althoff, Mark J., Cancelas, Jose A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709869/
https://ncbi.nlm.nih.gov/pubmed/31453073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40778-018-0128-6
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