Llwytho...

CD28 Signaling Controls Metabolic Fitness of Pathogenic T Cells in Medium and Large Vessel Vasculitis

BACKGROUND: In giant cell arteritis (GCA), vessel-wall infiltrating CD4 T-cells and macrophages form tissue-destructive granulomatous infiltrates and the artery responds with a maladaptive response-to-injury; leading to intramural neoangiogenesis, intimal hyperplasia and luminal occlusion. Lesion-re...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Coll Cardiol
Prif Awduron: Zhang, Hui, Watanabe, Ryu, Berry, Gerald J., Nadler, Steven G., Goronzy, Jörg J., Weyand, Cornelia M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709860/
https://ncbi.nlm.nih.gov/pubmed/30975299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2019.01.049
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