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CD28 Signaling Controls Metabolic Fitness of Pathogenic T Cells in Medium and Large Vessel Vasculitis
BACKGROUND: In giant cell arteritis (GCA), vessel-wall infiltrating CD4 T-cells and macrophages form tissue-destructive granulomatous infiltrates and the artery responds with a maladaptive response-to-injury; leading to intramural neoangiogenesis, intimal hyperplasia and luminal occlusion. Lesion-re...
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| Vydáno v: | J Am Coll Cardiol |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6709860/ https://ncbi.nlm.nih.gov/pubmed/30975299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2019.01.049 |
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