Bacterial load and inflammatory response in sputum of alpha-1 antitrypsin deficiency patients with COPD

BACKGROUND: Airway inflammation may drive the progression of chronic obstructive pulmonary disease (COPD) associated with alpha-1 antitrypsin deficiency (AATD), but the relationship between airway microbiota and inflammation has not been investigated. METHODS: We studied 21 non-treated AATD (AATD-no...

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Detalhes bibliográficos
Publicado no:Int J Chron Obstruct Pulmon Dis
Main Authors: Balbi, Bruno, Sangiorgi, Claudia, Gnemmi, Isabella, Ferrarotti, Ilaria, Vallese, Davide, Paracchini, Elena, Delle Donne, Lorena, Corda, Luciano, Baderna, Paolo, Corsico, Angelo, Carone, Mauro, Brun, Paola, Cappello, Francesco, Ricciardolo, Fabio LM, Ruggeri, Paolo, Mumby, Sharon, Adcock, Ian M, Caramori, Gaetano, Di Stefano, Antonino
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709647/
https://ncbi.nlm.nih.gov/pubmed/31686800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S207203
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