Neutrophilic inflammation and IL‐8 levels in induced sputum of alpha‐1‐antitrypsin PiMZ subjects

BACKGROUND: Severe alpha‐1‐antitrypsin deficiency (AATD), due to homozygosity for the protease inhibitor (Pi) Z allele, is a genetic risk factor for chronic obstructive pulmonary disease (COPD). In a previous study the sputum of severe AATD subjects with airflow obstruction showed a pattern of cellu...

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Detalhes bibliográficos
Main Authors: Malerba, M, Ricciardolo, F, Radaeli, A, Torregiani, C, Ceriani, L, Mori, E, Bontempelli, M, Tantucci, C, Grassi, V
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Alpha-1-Antitrypsin Deficiency
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2104580/
https://ncbi.nlm.nih.gov/pubmed/16284217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2005.043471
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