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Neutrophilic inflammation and IL‐8 levels in induced sputum of alpha‐1‐antitrypsin PiMZ subjects
BACKGROUND: Severe alpha‐1‐antitrypsin deficiency (AATD), due to homozygosity for the protease inhibitor (Pi) Z allele, is a genetic risk factor for chronic obstructive pulmonary disease (COPD). In a previous study the sputum of severe AATD subjects with airflow obstruction showed a pattern of cellu...
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主要な著者: | , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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BMJ Group
2006
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2104580/ https://ncbi.nlm.nih.gov/pubmed/16284217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2005.043471 |
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