A cysteinyl-tRNA synthetase variant confers resistance against selenite toxicity and decreases selenocysteine misincorporation

Selenocysteine (Sec) is the 21st genetically encoded amino acid in organisms across all domains of life. Although structurally similar to cysteine (Cys), the Sec selenol group has unique properties that are attractive for protein engineering and biotechnology applications. Production of designer pro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Hoffman, Kyle S., Vargas-Rodriguez, Oscar, Bak, Daniel W., Mukai, Takahito, Woodward, Laura K., Weerapana, Eranthie, Söll, Dieter, Reynolds, Noah M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2019
Gaiak:
Protein Synthesis and Degradation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709638/
https://ncbi.nlm.nih.gov/pubmed/31296657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008219
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