Delayed recanalization at 3 days after permanent MCAO attenuates neuronal apoptosis through FGF21/FGFR1/PI3K/Caspase-3 pathway in rats

Reperfusion exceeded time window may induce ischemia/reperfusion injury, increase hemorrhagic transformation, and deteriorate neurological outcomes in ischemic stroke models. However, the increasing clinical evidences supported that reperfusion even within 6–24 hours may salvage ischemic tissue and...

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Dettagli Bibliografici
Pubblicato in:Exp Neurol
Autori principali: Zheng, Wen, Matei, Nathanael, Pang, Jinwei, Luo, Xu, Song, Zhi, Tang, Jiping, Zhang, John H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709598/
https://ncbi.nlm.nih.gov/pubmed/31295445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.113007
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