Acquisition of Cross-Resistance to Bedaquiline and Clofazimine following Treatment for Tuberculosis in Pakistan

We report on the first six cases of acquired resistance to bedaquiline in Pakistan. Seventy sequential isolates from 30 drug-resistant-tuberculosis patients on bedaquiline-containing regimens were retrospectively tested for bedaquiline resistance by MIC testing and by the detection of mutations in r...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ghodousi, Arash, Rizvi, Alamdar Hussain, Baloch, Aurangzaib Quadir, Ghafoor, Abdul, Khanzada, Faisal Masood, Qadir, Mehmood, Borroni, Emanuele, Trovato, Alberto, Tahseen, Sabira, Cirillo, Daniela Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709449/
https://ncbi.nlm.nih.gov/pubmed/31262765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00915-19
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