Acquisition of Cross-Resistance to Bedaquiline and Clofazimine following Treatment for Tuberculosis in Pakistan

We report on the first six cases of acquired resistance to bedaquiline in Pakistan. Seventy sequential isolates from 30 drug-resistant-tuberculosis patients on bedaquiline-containing regimens were retrospectively tested for bedaquiline resistance by MIC testing and by the detection of mutations in r...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Ghodousi, Arash, Rizvi, Alamdar Hussain, Baloch, Aurangzaib Quadir, Ghafoor, Abdul, Khanzada, Faisal Masood, Qadir, Mehmood, Borroni, Emanuele, Trovato, Alberto, Tahseen, Sabira, Cirillo, Daniela Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709449/
https://ncbi.nlm.nih.gov/pubmed/31262765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00915-19
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