Synthesis, characterization, and mechanistic studies of a gold nanoparticle–amphotericin B covalent conjugate with enhanced antileishmanial efficacy and reduced cytotoxicity

BACKGROUND: Amphotericin B (AmB) as a liposomal formulation of AmBisome is the first line of treatment for the disease, visceral leishmaniasis, caused by the parasite Leishmania donovani. However, nephrotoxicity is very common due to poor water solubility and aggregation of AmB. This study aimed to...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Int J Nanomedicine
Asıl Yazarlar: Kumar, Prakash, Shivam, Pushkar, Mandal, Saptarshi, Prasanna, Pragya, Kumar, Saurabh, Prasad, Surendra Rajit, Kumar, Ashish, Das, Prolay, Ali, Vahab, Singh, Shubhankar Kumar, Mandal, Debabrata
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove 2019
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709383/
https://ncbi.nlm.nih.gov/pubmed/31686803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S196421
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller