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Mahanine exerts in vitro and in vivo antileishmanial activity by modulation of redox homeostasis

Earlier we have established a carbazole alkaloid (mahanine) isolated from an Indian edible medicinal plant as an anticancer agent with minimal effect on normal cells. Here we report for the first time that mahanine-treated drug resistant and sensitive virulent Leishmania donovani promastigotes under...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Roy, Saptarshi, Dutta, Devawati, Satyavarapu, Eswara M., Yadav, Pawan K., Mandal, Chhabinath, Kar, Susanta, Mandal, Chitra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482887/
https://ncbi.nlm.nih.gov/pubmed/28646156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03943-y
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