CD4(+)CD25(+)Foxp3(+) regulatory T cells suppress NKG2D-mediated NK cell cytotoxicity in peripheral blood

BACKGROUND: Studies have shown that CD4(+)CD25(+)Foxp3(+)Treg cells suppress NKG2D expression on NK cells via a cell contact-dependent mechanism and increased TGF-β and IL-10 production in some cancer models. We herein aimed to explore whether CD4(+)CD25(+)Foxp3(+)Tregs suppress NKG2D-mediated NK ce...

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Dettagli Bibliografici
Pubblicato in:Medicine (Baltimore)
Autori principali: Geng, Xu, Li, Ming, Cui, Bin, Lu, Chao, Liu, Xiaowen, Zhang, Peng, Liu, Bin, Ma, Chunyan, Shen, Yajuan, Lu, Zhiming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wolters Kluwer Health 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708973/
https://ncbi.nlm.nih.gov/pubmed/31145286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000015722
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