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Alterations of peripheral CD4(+)CD25(+)Foxp3(+) T regulatory cells in mice with STZ-induced diabetes

Complications arising from abnormal immune responses are the major causes of mortality and morbidity in diabetic patients. CD4(+)CD25(+) T regulatory cells (Tregs) play pivotal roles in controlling immune homeostasis, immunity and tolerance. The effect of hyperglycemia on CD4(+)CD25(+) Tregs has not...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhen, Yu, Sun, Lina, Liu, He, Duan, Kaizhong, Zeng, Chun, Zhang, Lianjun, Jin, Di, Peng, Jianxia, Ding, Wenjun, Zhao, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002930/
https://ncbi.nlm.nih.gov/pubmed/21983870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2011.37
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