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Schlafen 11 (SLFN11), a restriction factor for replicative stress induced by DNA-targeting anti-cancer therapies

Schlafen 11 (SLFN11) sensitizes cells to a broad range of anti-cancer drugs including platinum derivatives (cisplatin and carboplatin), inhibitors of topoisomerases (irinotecan, topotecan, doxorubicin, daunorubicin, mitoxantrone and etoposide), DNA synthesis inhibitors (gemcitabine, cytarabine, hydr...

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Bibliografski detalji
Izdano u:Pharmacol Ther
Glavni autori: Murai, Junko, Thomas, Anish, Miettinen, Markku, Pommier, Yves
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708787/
https://ncbi.nlm.nih.gov/pubmed/31128155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2019.05.009
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