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The Molecular Determinants of Neurosteroid Binding in the GABA(A) Receptor
Neurosteroids positively modulate GABA-A receptor (GABA(A)R) channel activity by binding to a transmembrane domain intersubunit site. Understanding the interactions in this site that determine neurosteroid binding and its effect is essential for the design of neurosteroid-based therapeutics. Using p...
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| Publicado no: | J Steroid Biochem Mol Biol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6708749/ https://ncbi.nlm.nih.gov/pubmed/31150831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2019.105383 |
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