Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway

Sestrin 3 (Sesn3) belongs to a small protein family that has been implicated in multiple biological processes including anti-oxidative stress, anti-aging, cell signaling, and metabolic homeostasis. However, the role of Sesn3 in hepatocellular carcinoma (HCC) remains unclear. Here we generated a Sesn...

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Bibliografske podrobnosti
izdano v:Biochim Biophys Acta Mol Basis Dis
Main Authors: Liu, Yunjian, Kim, Hyeong Geug, Dong, Edward, Dong, Chuanpeng, Huang, Menghao, Liu, Yunlong, Liangpunsakul, Suthat, Dong, Xiaocheng Charlie
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708743/
https://ncbi.nlm.nih.gov/pubmed/31351129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2019.07.011
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