Modelling pathogen load dynamics to elucidate mechanistic determinants of host-Plasmodium falciparum interactions

During infection, increasing pathogen load stimulates both protective and harmful aspects of the host response. The dynamics of this interaction are hard to quantify in humans, but doing so could improve understanding of mechanisms of disease and protection. We sought to model the contributions of p...

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Publicat a:Nat Microbiol
Autors principals: Georgiadou, Athina, Lee, Hyun Jae, Walther, Michael, van Beek, Anna E., Fitriani, Fadlila, Wouters, Diana, Kuijpers, Taco W., Nwakanma, Davis, D'Alessandro, Umberto, Riley, Eleanor M., Otto, Thomas D., Ghani, Azra, Levin, Michael, Coin, Lachlan J., Conway, David J., Bretscher, Michael T., Cunnington, Aubrey J.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708439/
https://ncbi.nlm.nih.gov/pubmed/31209307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0474-x
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