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Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

The pathogenesis of infectious diseases depends on the interaction of host and pathogen. In Plasmodium falciparum malaria, host and parasite processes can be assessed by dual RNA-sequencing of blood from infected patients. Here we performed dual transcriptome analyses on samples from 46 malaria-infe...

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發表在:Sci Transl Med
Main Authors: Lee, Hyun Jae, Georgiadou, Athina, Walther, Michael, Nwakanma, Davis, Stewart, Lindsay B., Levin, Michael, Otto, Thomas D., Conway, David J., Coin, Lachlan J., Cunnington, Aubrey J.
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326353/
https://ncbi.nlm.nih.gov/pubmed/29950443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aar3619
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