Complement Factor H Levels Associate With Plasmodium falciparum Malaria Susceptibility and Severity

BACKGROUND: Plasmodium falciparum may evade complement-mediated host defense by hijacking complement Factor H (FH), a negative regulator of the alternative complement pathway. Plasma levels of FH vary between individuals and may therefore influence malaria susceptibility and severity. METHODS: We me...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: van Beek, Anna E, Sarr, Isatou, Correa, Simon, Nwakanma, Davis, Brouwer, Mieke C, Wouters, Diana, Secka, Fatou, Anderson, Suzanne T B, Conway, David J, Walther, Michael, Levin, Michael, Kuijpers, Taco W, Cunnington, Aubrey J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059171/
https://ncbi.nlm.nih.gov/pubmed/30087905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy166
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