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DNA probes that store mechanical information reveal transient piconewton forces applied by T cells

The advent of molecular tension probes for real-time mapping of piconewton forces in living systems has had a major impact on mechanobiology. For example, DNA-based tension probes have revealed roles for mechanics in platelet, B cell, T cell, and fibroblast function. Nonetheless, imaging short-lived...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ma, Rong, Kellner, Anna V., Ma, Victor Pui-Yan, Su, Hanquan, Deal, Brendan R., Brockman, Joshua M., Salaita, Khalid
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708336/
https://ncbi.nlm.nih.gov/pubmed/31391300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904034116
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