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Platelet integrins exhibit anisotropic mechanosensing and harness piconewton forces to mediate platelet aggregation
Platelet aggregation at the site of vascular injury is essential in clotting. During this process, platelets are bridged by soluble fibrinogen that binds surface integrin receptors. One mystery in the mechanism of platelet aggregation pertains to how resting platelets ignore soluble fibrinogen, the...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5777034/ https://ncbi.nlm.nih.gov/pubmed/29269394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710828115 |
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