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Oxidative Amide Coupling from Functionally Diverse Alcohols and Amines using Aerobic Copper/Nitroxyl Catalysis
The aerobic Cu/ABNO catalyzed oxidative coupling of alcohols and amines is highlighted here in the synthesis of amide bonds in diverse drug-like molecules (ABNO = 9-azabicyclo[3.3.1]nonane N-oxyl). The robust method leverages the privileged reactivity of alcohols bearing electronegative heteroatoms...
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| 出版年: | Angew Chem Int Ed Engl |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6707856/ https://ncbi.nlm.nih.gov/pubmed/31206988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201906130 |
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