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Loss of p53 triggers Wnt-dependent systemic inflammation to drive breast cancer metastasis
Cancer-associated systemic inflammation is strongly linked with poor disease outcome in cancer patients(1,2). For most human epithelial tumour types, high systemic neutrophil-to-lymphocyte ratios are associated with poor overall survival(3), and experimental studies have demonstrated a causal relati...
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| Опубликовано в: : | Nature |
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| Главные авторы: | , , , , , , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6707815/ https://ncbi.nlm.nih.gov/pubmed/31367040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1450-6 |
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