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Hepatic SIRT3 Upregulation in Response to Chronic Alcohol Consumption Contributes to Alcoholic Liver Disease in Mice
BACKGROUND: Alcoholic liver disease (ALD) is a type of chronic liver disease caused by chronic ethanol overconsumption. The pathogenesis of ALD is complex and there is no effective clinical treatment thus far. SIRT3 is an NAD(+)-dependent deacetylase primarily located inside mitochondria, and report...
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| Izdano u: | Front Physiol |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6707764/ https://ncbi.nlm.nih.gov/pubmed/31474877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01042 |
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