The reduction of XIAP is associated with inflammasome activation in RPE: implications for AMD pathogenesis

BACKGROUND: Age-related macular degeneration (AMD) is a multifactorial chronic disease of the eye. Several candidate pathways have been hypothesized to play a role in AMD pathogenesis. Our work and those of others suggests inflammasome activity as a mechanism associated with retinal pigment epitheli...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Gao, Jiangyuan, Cui, Jing Z., Wang, Aikun, Chen, Hao Hang Rachel, Fong, Alison, Matsubara, Joanne A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706877/
https://ncbi.nlm.nih.gov/pubmed/31438981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1558-5
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