Inflammatory Mediators Induced by Amyloid-Beta in the Retina and RPE In Vivo: Implications for Inflammasome Activation in Age-Related Macular Degeneration

PURPOSE: Drusen are hallmarks of age-related macular degeneration (AMD). Amyloid-beta 1-40 (Aβ 1-40), a constituent of drusen, is known to stimulate inflammatory pathways in RPE; however, its effect in vivo is not known. The purpose of this study was to examine the effect of Aβ 1-40 on cytokine expr...

Full description

Saved in:
Bibliographic Details
Main Authors: Liu, Ruozhou Tom, Gao, Jiangyuan, Cao, Sijia, Sandhu, Navroop, Cui, Jing Z., Chou, Chai Lin, Fang, Edward, Matsubara, Joanne A.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947398/
https://ncbi.nlm.nih.gov/pubmed/23462752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10849
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items