Inflammatory Mediators Induced by Amyloid-Beta in the Retina and RPE In Vivo: Implications for Inflammasome Activation in Age-Related Macular Degeneration

PURPOSE: Drusen are hallmarks of age-related macular degeneration (AMD). Amyloid-beta 1-40 (Aβ 1-40), a constituent of drusen, is known to stimulate inflammatory pathways in RPE; however, its effect in vivo is not known. The purpose of this study was to examine the effect of Aβ 1-40 on cytokine expr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Ruozhou Tom, Gao, Jiangyuan, Cao, Sijia, Sandhu, Navroop, Cui, Jing Z., Chou, Chai Lin, Fang, Edward, Matsubara, Joanne A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947398/
https://ncbi.nlm.nih.gov/pubmed/23462752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10849
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