Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia

Alterations in global DNA methylation patterns are a major hallmark of cancer and represent attractive biomarkers for personalized risk stratification. Chronic lymphocytic leukemia (CLL) risk stratification studies typically focus on time to first treatment (TTFT), time to progression (TTP) after tr...

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Vydáno v:Blood
Hlavní autoři: Giacopelli, Brian, Zhao, Qiuhong, Ruppert, Amy S., Agyeman, Akwasi, Weigel, Christoph, Wu, Yue-Zhong, Gerber, Madelyn M., Rabe, Kari G., Larson, Melissa C., Lu, Junyan, Blachly, James S., Rogers, Kerry A., Wierda, William G., Brown, Jennifer R., Rai, Kanti R., Keating, Michael, Rassenti, Laura Z., Kipps, Thomas J., Zenz, Thorsten, Shanafelt, Tait D., Kay, Neil E., Abruzzo, Lynne V., Coombes, Kevin R., Woyach, Jennifer A., Byrd, John C., Oakes, Christopher C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2019
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706807/
https://ncbi.nlm.nih.gov/pubmed/31292113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019000490
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