Characterization of Novel Fragment Antibodies Against TNF-alpha Isolated Using Phage Display Technique

Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine which plays crucial roles in pathogenesis of inflammatory diseases. The current study aimed to investigate the binding abilities of I44 and I49 domain antibodies to TNF-α. The dAbs were expressed in bacterial expression system and purif...

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Detalles Bibliográficos
Publicado en:Iran J Pharm Res
Autores principales: Alizadeha, Ali Akbar, Hamzeh-Mivehroud, Maryam, Haddad, Elnaz, Haddad, Nazanin, Sharifi, Mehdi, Mohammadi, Samin, Pourtaghi-anvarian, Samira, Dastmalchi, Siavoush
Formato: Artigo
Lenguaje:Inglês
Publicado: Shaheed Beheshti University of Medical Sciences 2019
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706722/
https://ncbi.nlm.nih.gov/pubmed/31531059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2019.1100646
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