Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation

Controlling responsiveness to prevailing signals is critical for robust transitions between cell states during development. For example, fibroblast growth factor (FGF) drives naive pluripotent cells into extraembryonic lineages before implantation but sustains pluripotency in primed cells of the pos...

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Udgivet i:Dev Cell
Main Authors: Malaguti, Mattias, Migueles, Rosa Portero, Blin, Guillaume, Lin, Chia-Yi, Lowell, Sally
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706657/
https://ncbi.nlm.nih.gov/pubmed/31204172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.05.032
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