Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation

Controlling responsiveness to prevailing signals is critical for robust transitions between cell states during development. For example, fibroblast growth factor (FGF) drives naive pluripotent cells into extraembryonic lineages before implantation but sustains pluripotency in primed cells of the pos...

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Publicat a:Dev Cell
Autors principals: Malaguti, Mattias, Migueles, Rosa Portero, Blin, Guillaume, Lin, Chia-Yi, Lowell, Sally
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706657/
https://ncbi.nlm.nih.gov/pubmed/31204172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.05.032
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