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A method to induce hen egg lysozyme-specific humoral immune tolerance in mice by pre-exposition with the protein's oligomers

During treatment with protein therapeutics, such as monoclonal antibodies, the development of anti-drug antibodies is a serious side-effect of modern pharmacology. Anti-drug antibodies are produced as the number and exposure to therapeutic proteins increase. In this context, less immunogenic respons...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Ohkuri, Takatoshi, Yuge, Natsuko, Sato, Kenji, Ueda, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706346/
https://ncbi.nlm.nih.gov/pubmed/31463374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2019.100679
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